nieuwe zoekopdracht
[ meld een fout in dit record ]mandje (0): toevoegen | toon Print deze pagina

Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes
Eme, Laura; Tamarit, Daniel; Caceres, Eva F.; Stairs, Courtney W.; De Anda, Valerie; Schön, Max E.; Seitz, Kiley W.; Dombrowski, Nina; Lewis, William H.; Homa, Felix; Saw, Jimmy H.; Lombard, Jonathan; Nunoura, Takuro; Li, Wen-Jun; Hua, Zheng-Shuang; Chen, Lin-Xing; Banfield, Jillian F.; John, Emily St; Reysenbach, Anna-Louise; Stott, Matthew B.; Schramm, Andreas; Kjeldsen, Kasper U.; Teske, Andreas P.; Baker, Brett J.; Ettema, Thijs J. G. (2023). Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes. Nature (Lond.) 618(7967): 992-999.
In: Nature: International Weekly Journal of Science. Nature Publishing Group: London. ISSN 0028-0836; e-ISSN 1476-4687, meer
Peer reviewed article  

Beschikbaar in  Auteur 

Author keywords
    Archaeal evolution; Metagenomics; Phylogenetics

Auteur  Top 
  • Dombrowski, N., meer

    In the ongoing debates about eukaryogenesis—the series of evolutionary events leading to the emergence of the eukaryotic cell from prokaryotic ancestors—members of the Asgard archaea play a key part as the closest archaeal relatives of eukaryotes. However, the nature and phylogenetic identity of the last common ancestor of Asgard archaea and eukaryotes remain unresolved. Here we analyse distinct phylogenetic marker datasets of an expanded genomic sampling of Asgard archaea and evaluate competing evolutionary scenarios using state-of-the-art phylogenomic approaches. We find that eukaryotes are placed, with high confidence, as a well-nested clade within Asgard archaea and as a sister lineage to Hodarchaeales, a newly proposed order within Heimdallarchaeia. Using sophisticated gene tree and species tree reconciliation approaches, we show that analogous to the evolution of eukaryotic genomes, genome evolution in Asgard archaea involved significantly more gene duplication and fewer gene loss events compared with other archaea. Finally, we infer that the last common ancestor of Asgard archaea was probably a thermophilic chemolithotroph and that the lineage from which eukaryotes evolved adapted to mesophilic conditions and acquired the genetic potential to support a heterotrophic lifestyle. Our work provides key insights into the prokaryote-to-eukaryote transition and a platform for better understanding the emergence of cellular complexity in eukaryotic cells.

Alle informatie in het Integrated Marine Information System (IMIS) valt onder het VLIZ Privacy beleid Top | Auteur 
IMIS is ontwikkeld en wordt gehost door het VLIZ, voor meer informatie contacteer .