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Pharmacological and chemical properties of some marine echinoderms
Marmouzi, I.; Tamsouri, N.; El Hamdani, M.; Attar, A.; Kharbach, M.; Alami, R.; El Jemli, M.; Cherrah, Y.; Ebada, S.S.; Faouzi, M.E.A. (2018). Pharmacological and chemical properties of some marine echinoderms. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy 28(5): 575-581. https://hdl.handle.net/10.1016/j.bjp.2018.05.015
In: Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy: Curitiba. ISSN 0102-695X
Peer reviewed article  

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Trefwoorden
    Echinodermata [WoRMS]
    Marien
Author keywords
    Echinoderms; Phenolic; alpha-Amylase; alpha-Glucosidase; Antimicrobial

Auteurs  Top 
  • Marmouzi, I.
  • Tamsouri, N.
  • El Hamdani, M.
  • Attar, A.
  • Kharbach, M.
  • Alami, R.
  • El Jemli, M.
  • Cherrah, Y.
  • Ebada, S.S.
  • Faouzi, M.E.A.

Abstract
    Echinoderms have attracted the attention of scientists over the past few years after identifying a variety of unique structures endowed by interesting biological properties. However, the Moroccan coast biodiversity is still uninvestigated. In our ongoing attempts to valorize the rich Moroccan marine environment, this study aimed at assessing the antimicrobial activity of extracts obtained from three echinoderms Astropecten irregularis, Luidia sarsi and Ophiura albida against the human pathogens: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica and Bacillus subtilis. Moreover, their antioxidant activities were tested using standard methods in addition to the antidiabetic activity which has been evaluated in vitro against α-amylase and α-glucosidase enzymes. HPLC-DAD-QTOF-MS analysis revealed a significant content of some phenolic compounds such as pyrogallol, gallic, sinapic, ferulic, p-hydroxybenzoic and salicylic acids whose existence can be related to the endophytic fungi and/or dietary intake whereas GC-MS analysis exhibited diverse chemical structures such as cholesterol, oleic acid and glycerol 1-palmitate.

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