nieuwe zoekopdracht
[ meld een fout in dit record ]mandje (0): toevoegen | toon Print deze pagina

Effects of PCBs on reactive oxygen species (ROS) production by the immune cells of Paracentrotus lividus (Echinodermata)
Coteur, G.; Danis, B.; Fowler, S.W.; Teyssie, J.L.; Dubois, P.; Warnau, M. (2001). Effects of PCBs on reactive oxygen species (ROS) production by the immune cells of Paracentrotus lividus (Echinodermata). Mar. Pollut. Bull. 42(8): 667-672. dx.doi.org/10.1016/S0025-326X(01)00063-7
In: Marine Pollution Bulletin. Macmillan: London. ISSN 0025-326X; e-ISSN 1879-3363, meer
Peer reviewed article  

Beschikbaar in  Auteurs 

Trefwoord
    Marien
Author keywords
    polychlorinated biphenyls; immune system; reactive oxygen species;

Auteurs  Top 
  • Coteur, G.
  • Danis, B.
  • Fowler, S.W.
  • Teyssie, J.L.
  • Dubois, P.
  • Warnau, M.

Abstract
    The impact of four PCB congeners: 3,3',4,4'-tetrachlorobiphenyl (IUPAC congener #77), 3,3',4,4',5-pentachlorobiphenyl (IUPAC #126), 2,2',4,4',5,5'-hexachlorobiphenyl (IUPAC #153) and 3,3',4,4',5,5'-hexachlorobiphenyl (IUPAC #169) was investigated on the reactive oxygen species (ROS) production by coelomocytes of the echinoid Paracentrotus lividus, an important species in marine benthic ecosystems. PCBs were found to increase ROS production and to delay the time of peak production. These effects were stronger on bacteria-stimulated cells and were congener-specific: coplanar congeners (#77, 126 and 169) had more effect than the non-coplanar PCB #153. Among coplanar congeners, PCB #169 showed dose-dependent effects whereas PCB #77 and 126 were more toxic at high and low doses, respectively. The relative immunotoxicity of the different PCB congeners is discussed in the light of their structural properties and biological affinities.

Alle informatie in het Integrated Marine Information System (IMIS) valt onder het VLIZ Privacy beleid Top | Auteurs 
IMIS is ontwikkeld en wordt gehost door het VLIZ, voor meer informatie contacteer .