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Accumulation and elimination of 14C-gamma-HCH (lindane) in Nereis virens (Polychaeta) with consideration of metabolites
Goerke, H.; Ernst, W. (1980). Accumulation and elimination of 14C-gamma-HCH (lindane) in Nereis virens (Polychaeta) with consideration of metabolites, in: Kinne, O. et al. (Ed.) Protection of life in the sea: 14th European Marine Biology Symposium, 23-29 September 1979, Helgoland. Helgoländer Meeresuntersuchungen, 33(1-4): pp. 313-326
In: Kinne, O.; Bulnheim, H.-P. (Ed.) (1980). Protection of life in the sea: 14th European Marine Biology Symposium, 23-29 September 1979, Helgoland. Helgoländer Meeresuntersuchungen, 33(1-4). Biologische Anstalt Helgoland: Hamburg. 772 pp.
In: Helgoländer Meeresuntersuchungen. Biologische Anstalt Helgoland: Hamburg. ISSN 0174-3597
Peer reviewed article  

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Documenttype: Congresbijdrage

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  • Goerke, H.
  • Ernst, W.

Abstract
    In two experiments, conducted at 6° and 16 °C, 43 Nereis virens were exposed to14C-labelled ?-HCH (lindane) at a concentration of 1 µg/l, which was maintained by intermittent monitoring and redosing. A closed system with individuals living in glass tubes was used. At equilibrium and during the subsequent phase of elimination, both ?-HCH and metabolites were determined in individual worms as well as in the water and faeces throughout the entire experiment. The bioconcentration factors of ?-HCH were 480 and 440 at 6° and 16 °C, respectively; those based on total radioactivity were 500 and 410. These factors were in the upper range of those known for other aquatic animals. The elimination may be described by an exponential function. The initial 50% decrease of ?-HCH and ?-HCH+metabolites in the worms occurred at both temperatures in 2 and 3 days, respectively. The percentage of ?-HCH metabolites in worms increased considerably during the elimination period. At least four metabolites were detected in worms and water. If pollutants are evaluated by accumulation and elimination kinetics, metabolization has to be taken into account.

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